North Carolina (NC) — What’s Legal

Checked Oct 13 2025 • Parent-friendly summary (not legal advice).

Tianeptine: Schedule II effective Dec 1 2024.
Phenibut: Not scheduled; FDA says not a lawful dietary ingredient.
Kratom: Moving to 21+/labeling framework (2025 bill pending); local rules vary.
Nitrous oxide: Possession for intoxication illegal (G.S. §90-113.10).
THC / Cannabis: No medical or adult-use program; hemp products sold under federal allowance.
Salvia: Illegal to manufacture/sell/possess (statewide ban).
Amanita muscaria: Not scheduled.
“Mad honey”: No NC-specific ban; FDA warns on grayanotoxins.

Parent tip: NC now treats tianeptine like an opioid — report stores still selling “gas-station heroin.” Keep kids away from kratom shots.