Ohio (OH) — What’s Legal

Checked Oct 13, 2025 • Parent-friendly summary (not legal advice).

Tianeptine: Schedule I — OAC 4729:9-1-01 lists “Tianeptine.”
Phenibut: Not scheduled; FDA: not a lawful dietary ingredient.
Kratom: Scheduling press intensified Aug–Sep 2025; action pending/contested. Natural kratom not yet on OH Schedule I — watch rule filings.
Nitrous oxide / inhalants: ORC § 2925.32 restricts sales/devices and certain conduct tied to N₂O; targeted enforcement occurs.
THC / Cannabis: Adult-use legal (Issue 2, 2023); sales rollout underway via dual licensing from medical dispensaries.
Salvia: Ohio law references impairment/operating thresholds related to salvia/salvinorin A (evidence standards appear in ORC; distinct from IN).
Amanita muscaria: Not scheduled.
“Mad honey”: No OH-specific ban; FDA/CDC grayanotoxin hazard framing applies.

Parent tip: Kratom rules may change quickly in Ohio — avoid “enhanced 7-OH” products and watch official updates.