South Dakota (SD) — What’s Legal

Checked Oct 13, 2025 • Parent-friendly summary (not legal advice).

Tianeptine: No statewide schedule; local bans advancing (e.g., Rapid City ordinance).
Phenibut: Not scheduled; FDA: not a lawful dietary ingredient.
Kratom: 21+ & product limits (2025 law tightened 7-OH concentrations, labeling, adulterants).
Nitrous oxide / inhalants: General inhalant law; local retail restrictions possible.
THC / Cannabis: Medical program active; adult-use rejected by voters (Nov 2024).
Salvia / Amanita: Not scheduled statewide.
“Mad honey”: No SD-specific ban; food hazard framing.

Parent tip: Ask for age checks and for candy-look-alike packaging to be kept behind the counter.