Mitragynine (Kratom)
Total reports
733
Deaths
258
Hospitalizations
191
Serious cases
404
Top reported reactions (5)
- Death
- Dependence
- Toxicity to various agents
- Vomiting
- Withdrawal syndrome
Source: CAERS JSON (uploaded to MAHA).
Important context: CAERS is a spontaneous reporting system for foods and dietary supplements. Reports may be incomplete or duplicative and do not prove causation. They do help detect safety signals that deserve attention.
Tianeptine
Total reports
65
Deaths
9
Hospitalizations
28
Serious cases
47
Top reported reactions (5)
- Dependence
- Toxicity to various agents
- Confusional state
- Drug abuse
- Withdrawal syndrome
Source: CAERS JSON (uploaded to MAHA).
4-amino-3-phenylbutyric acid (Phenibut)
Total reports
22
Deaths
4
Hospitalizations
10
Serious cases
12
Top reported reactions (5)
- Loss of consciousness
- Tachycardia
- Mydriasis
- Blood pressure increased
- Poisoning
Note: often appears as “4-amino-3-phenylbutyric acid.” Source: CAERS JSON (uploaded to MAHA).
Amanita muscaria
Total reports
6
Deaths
0
Hospitalizations
1
Serious cases
1
Top reported reactions (5)
- Nausea
- Vomiting
- Hallucination
- Confusional state
- Dizziness
Source: CAERS JSON (uploaded to MAHA).
Mushroom hallucinogen (psilocybin/psilocin)
Total reports
28
Deaths
0
Hospitalizations
2
Serious cases
5
Top reported reactions (5)
- Hallucination
- Anxiety
- Nausea
- Vomiting
- Dizziness
Source: CAERS JSON (uploaded to MAHA).
Nitrous Oxide
Total reports
1
Deaths
0
Hospitalizations
1
Serious cases
1
Top reported reactions (5)
- Balance disorder
- Brain injury
- Central nervous system lesion
- Confusional state
- Cystitis
Source: CAERS JSON (uploaded to MAHA).
- Counts reflect what consumers/clinicians reported; one report can list multiple products and reactions.
- Under-reporting is common; media attention can drive spikes in reports.
- CAERS covers foods & dietary supplements (different scope than FAERS for drugs/devices).